Excerpt From University
Halliburton Endarterectomy Catheter
are investigating a novel atherectomy catheter, invented by Alexander Halliburton,
a local Alberta inventor.
Halliburton catheter has several design advantages over other available
atherectomy catheters and standard balloon angioplasty catheters. These
of design; the cut is performed by mechanical action requiring no high
speed rotating parts.
cutting edge moves forward at high speed to complete a plaque excision.
is no motor drive or cooling system, as there is no high speed rotation
involved in the mechanism.
catheter has a very low profile, with an outside diameter of 1.0 - 3.5
mm; the working model can be manufactured with plastic or stainless steel.
This catheter is therefore competitive with standard balloon angioplasty
assembly is extremely flexible and negotiates circuitous arteries well.
device can perform multiple cuts or excisions.
cost is low.
date we have successfully developed a prototype catheter capable of negotiating
and entering coronary arteries 1.0 - 3.5 mm in diameter. Atherosclerotic
plaque has been excised successfully from human coronary artery necropsy
specimens. Initial test of the catheter prototype have been completed,
in vitro, in specimens of human coronary arteries. Of the specimens 90%
demonstrated effective plaque excision on gross morphological examination.
To date the Halliburton atherectomy catheter has been successfully introduced
in to the aorta of eight normal roosters. The immediate angiographic examination
revealed minimal adverse effects. The long-term results are pending. The
first atherectomy procedure on an occluded femoral artery in a cholesterol
fed rooster has been performed.
In Vitro Assement
In Vivo Testing